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Glutamine deprivation [122] and the inhibition of GOT1 [123] or GOT2 [124, 125] increase intracellular ROS

While under normal circumstances the body can produce sufficient amounts of this amino acid, during periods of physical stress, illness, intense exercise, or injury, demand can exceed supply

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Single-cell analysis of both intracellular calcium signals and cell surface dynamics indicated that most cells exhibited at least one burst of intracellular calcium concomitant with the initiation of the RVD phase following hypotonicity challenge (Fig

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