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Reported side effects of injectable GHK-Cu include: Mild redness or irritation at the injection site Occasional bruising Mild nausea (rare) Temporary skin flushing Reported side effects of topical GHK-Cu include: Skin sensitivity or redness (usually mild and transient) Allergic reaction in individuals with copper sensitivity (rare) GHK-Cu doesn't affect hormone levels, blood sugar, blood pressure, or any major organ system function at therapeutic doses
Can copper peptides cause hyperpigmentation
Similarly, the American Diabetes Association recommends the use of GLP1RAs to treat individuals who are at high risk for CVD (121)