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GSK-3 inhibition however does not recapitulate all of the protective features of lithium (see Figure 1), and this raises the possibility that their combined use with drugs targeting non-GSK-3-dependent mechanisms of lithium action may exert more effective neuro-protection under accumulating damage in dementia

Su L, Xu R, Ren Y et al (2024) Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data

Additionally, surgical interventions often involve hardware, such as pins or plates, and carry risks including infection, stiffness, or recurrent instability

The phase of breaking through the mucosal wall, which is still a difficult task when administered by inhalation, can be avoided with intravenous administration for the treatment of respiratory disorders [25, 27]