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Edwards et al., Figure 1 (C) Reduction (detoxification) of fatty acid hydroperoxides to corresponding hydroxy derivatives by the peroxidase activity of GST as described by Bartling et al

But hes positive the theory that you know, and oxidative reactive oxygen species are released by the mitochondria to protect the cells from further damage in a dysfunctional cellular response, and it continues to be activated despite the neutralization of the threat and these reactive oxygen species act, dysfunctional, damaging healthy cells, and he says he had contrary to long held beliefs about the etiology of these diseases

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In this regard, mutations to NRF2 and its regulator KEAP1 have been found in cancer cells, supporting the supposition that antioxidant genes are pivotal in tumor progression 59,60,61,62