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Maintaining levels of activated folate may also aid in preventing depression.4-6 COMT (Catechol-O-methyltransferase) A common mutation in COMT, the conversion of the amino acid valine to methionine at positon 158 causes a dramatic reduction in its ability to break down neurotransmitters.7-9 Since COMT is central to dopamine metabolism, mutations are associated with lowered stress resiliency, increased sensitivity to pain10,11 and the propensity to worry

On top of good inhalable drug design, successful translation from bench to bedside requires addressing key clinical factors (Fig

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Studies have explored its potential to promote peripheral nerve regeneration after injury and to offer protection against the effects of various neurotoxins