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ATF4 protein is induced eIF2 phosphorylation-mediated translational inhibition 32,33

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AOD9604 From R1250 Quick links Protocols 1

This could be due to the essential nature of the currently identified TrxR target or suggest the compound has a larger impact and affects other cellular systems

Gan X, Chen B, Shen Z, Liu Y et al (2014) High GPX1 expression promotes esophageal squamous cell carcinoma invasion, migration, proliferation and cisplatin-resistance but can be reduced by vitamin D