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Am J Physiol 274 : C396C405

Supplements like CoQ10, resveratrol, and alpha-lipoic acid have demonstrated potential in supporting energy metabolism and reducing oxidative stress, both of which are essential for maintaining cellular vitality [38]

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

These modifications may cause an imbalance in the cells antioxidant defense system and these inflammatory factors homeostasis, which ultimately results in a pathophysiological malfunction and apoptosis [30]