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Combination of photodynamic therapy and a flagellin-adjuvanted cancer vaccine potentiated the anti-PD-1-mediated melanoma suppression

En particular, la glutatin reductasa pareciera ser una buena diana teraputica para la accin de antimalricos, ya que la glutatin reductasa del parsito Plasmodium falciparum es significativamente diferente en cuanto a estructura y plegamiento a la glutatin reductasa de los mamferos

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Furthermore, we show that targeting mitochondrial metabolism, particularly by inhibiting Complex I, sensitizes CRC cells to 5FU, resulting in delayed tumour growth and prolonged survival in preclinical models