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This is mainly caused by Candida and is usually associated with delayed diagnosis, a high incidence of acute exacerbation of chronic liver failure, prolonged hospital stay, admission to the intensive care unit, and a worse 30 day survival rate compared to no infection or bacterial infection 81,89

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iii) Autophagy may disrupt other mechanisms involved in CP nephrotoxicity, particularly apoptosis and oxidative stress

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The later onset of symptoms, shorter duration of disease, better mean BCVA at baseline, and higher mean EZ width suggest that cohort 3 subjects had less compromise of foveal cone structure and function than cohort 1 subjects