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This does not exclude potential effect of a smaller dose with an earlier timing that was identified as the most potential to correct a delayed rhythm in our systematic review in other populations [84]

These two mechanisms are complementary and don't overlap

This study answered that question with a clear yes and mapped the specific biological pathways involved

Cardiovascular benefits: Clinical trials have demonstrated that tirzepatide can reduce the risk of major adverse cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who have established cardiovascular disease

PEGDA, Poly ethylene glycol diacrylate