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These data, together with mechanistic work showing that insulin stimulates VEGF and IGF production while glucose primes macrophages for inflammatory cytokine release 394 , suggest that the combination of high glucose and high insulin is more deleterious than hyperglycemia alone

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Such findings suggest that MOTS-c might play a contributing role in healthy aging, especially in maintaining metabolic function and physical performance as organisms get older

And because of that, I find if they're training it at a high level Especially more the ironman kind of the extreme athletes

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