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The mechanism may be associated with the nature of Apo J binding to exposed hydrophobic domains during protein unfolding 68 , thus preventing the interaction hydrophobic surfaces-mediated interactions and subsequent aggregation of LDL particles 67,69

PHGDH enzyme: a novel target for cancer treatment The serine synthesis pathway has been widely reported to be strongly associated with cancer proliferation and metastasis, although the specific mechanism underpinning the functional addiction of some tumour cells to serine remains uncertain 11

& Harmsen, M

These enzymes use the energy of NTP hydrolysis to unwind double-stranded RNA, and NS3 unwinds RNA and DNA homoduplexes and heteroduplexes in a 3 to 5 direction 25