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Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma

However, because these residues appear to contact AGO2 in both protomers, interacting with the N and MID domains in the cases of ZSWIM8 NPAZ and ZSWIM8 MID , respectively, the contributions of these potentially bifunctional residues could not be assigned to a single protomer