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Science 292 : 727730 Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP and Ron D (2000) Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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[DOI] [PubMed] [Google Scholar] 104.Miyazaki I., Isooka N., Imafuku F., Sun J., Kikuoka R., Furukawa C., Asanuma M

Since each of the tested reducing agents/thiols blocked melanin production, it is conceivable that accumulation of thiols directly upstream of Gsh2 (-Glu-Cys and cysteine) could contribute to the enhanced redox buffering and/or lack of melanin in gsh2 mutants, likely through diversion to other metabolic pathways

Links (lines) between the nodes represent significant similarity in activation patterns relative to shuffled data