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So an international panel, made up of clinicians, people living with chronic spine pain, and research methodologists, carried out a detailed analysis of the latest evidence using the GRADE approach (a system used to assess the quality of evidence)

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Other people may become B12 deficient if they lack certain gut enzymes that allow the body to 'extract' B12 for animal sources

Metformin interferes with the absorption of vitamin B12 in the small intestine, which over time may lead to a deficiencyespecially if the drug is taken for several years