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These findings offer a biological basis to link maternal B-vitamin status with neurodevelopment of the offspring, but more thorough investigation of these diet-epigenome-brain relationships is currently ongoing within the international EpiBrain project, involving partners in the UK, Canada and Spain, with the aim of providing substantiation and translation of the evidence for health improvement strategies (Reference Caffrey, Lamers and Murphy132)

2023 May 9;9(1):47

Abstract Expression of affinity-tagged recombinant proteins for crystallography, proteinprotein interaction, antibody generation, therapeutic applications, etc

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In the study by Fontcuberta-PiSunyer et al., human fibroblasts were directly reprogrammed using adenoviral vectors delivering NEUROG3, PDX1, and MAFA, followed sequentially by PAX4 and NKX2-2