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219,220,221 MYC is a commonly occurring oncogene, 222 yet the metabolic characteristics of tumors with high MYC expression are still worth exploring

Combined therapy of iron chelator and antioxidant completely restores brain dysfunction induced by iron toxicity

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An -hydroxy acid sometimes produced at high levels by cancer cells, which structurally resembles -ketoglutarate and so inhibits -ketoglutarate-dependent enzymes such as the Jumonji-family histone demethylases