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Lipid deposition also causes changes in the expression of intercellular tight junction proteins (JAM, Occludin, and Claudin), which increases the permeability of the blood-retinal barrier and the infiltration of plasma components into the retina, causing changes in retinal structure

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Clones were collected and grown in media containing 300 M CuSO 4 and subject to galactose selection

Our study implicates that targeting the estrogen-dependent system x c , specifically SLC7A11 and SLC3A2, with IKE through induction of ferroptosis in ER+ breast cancer cells, should offer a new therapeutic option for patients with ER+ breast cancer, particularly those with endocrine resistance

In this regard, the contribution of oxidants to muscle fatigue has been studied using a variety of animal models via in vitro and in situ muscle preparations and during exercise in intact animals