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The integration of glutathione homeostasis and redox signaling

The authors demonstrated that supplementation with alanyl-glutamine at a dose of 0.5 g/kg of BW per day, starting before the surgical procedure and continuing for 1 day postoperatively, could compensate for the inhibitory effects on arginine production resulting from ischemia-reperfusion injury to the kidneys

NAC is a widely used, general ROS scavenger that acts as a precursor of glutathione synthesis and stimulates certain enzymes involved in glutathione regeneration 15

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