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18 Continued efficacy was confirmed in a similar study in which Psoriasis Area and Severity Index (PASI) score improvements of at least 50%, 75%, and 90% was shown to be achieved by increasing percentages of participants over a period of years

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For a detailed breakdown of how these compounds differ individually, see our retatrutide vs tirzepatide vs semaglutide comparison, which covers receptor profiles, trial data, and research applications for each compound