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Biological evaluations were conducted using human hepatocarcinoma cell line (HepG2 cells) under two conditions: glucose-containing and glucose-free (galactose-supplemented) media to model mitochondrial toxicity

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Oxidative stress from superoxide production was determined by DHE in sections from all groups in the presence or absence of the inhibitors L-NAME or PEGSOD and the fluorescence quantified by automated image analysis

These NPs carried mRNA encoding IL12, a potent Tcellactivating cytokine

Neurology December 13, 2005 vol