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doi: 10.1021/acscentsci.6b00199 75 KroemerG.GalluzziL.VandenabeeleP.AbramsJ.AlnemriE

Watermelon has been shown to significantly reduce BP, likely through endothelium-dependent vasodilation due to its high L-citrulline content, which is converted to L-arginine (232)

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Nrf2 regulates important genes such as heme-oxygenase 1(HO-1), glutathione S-transferase (GST), glutathione reductase (GR), glutamate-cysteine ligase subunits (GCLc and GCLm), NAD(P)H quinone oxidoreductase-1 (NQO1), and thioredoxins (TrxR1), among others

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