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Lac-phe helps reduce hunger

Jan 2008;14(1):1-6

doi:10.7860/JCDR/2016/18208.8127 9 Manchikanti L, Buenaventura RM, Manchikanti KN, et al

However, mRNA levels of neurotrophic factors, including IGF-I, GDNF, BDNF, and anti-inflammatory factors were decreased in the spinal cords of SOD1 G93A /RAG2 / and SOD1 G93A /CD4 / mice, as were the levels of CX3CR1 and several glutamate receptors

Several other studies (one of them being a large scale community-based Framingham Heart Study [221]) have suggested a role for IGF-1 in the prevalence of insulin resistance and MetS [221223]