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Although Circular ASAP2 mediates DN, nothing is known about its biological mechanism and function

Following its translocation from the endoplasmic reticulum to perinuclear vesicles, activated STING enlists and activates TANK-binding kinase 1 (TBK1) [218]

and the general neglect of the potential cell-specific functions of AhR signaling across different liver cell populations (e.g., hepatocytes, stellate cells)