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Indian J Urol 31(1):5764 Peng C, Cheng Q, Liu Y et al (2022) Marginal zinc deficiency in mice increased the number of abnormal sperm and altered the expression level of spermatogenesis-related genes

Collectively, these findings emphasize the multifactorial and hormone-sensitive nature of perimenopausal mood disorders, shaped by complex interactions among E2, progesterone, neurosteroids, neurotransmitters and neuroendocrine stress systems