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It added that colon cleansing procedures, or enemas, a common method of detoxing, "may have side effects, some of which can be serious." An enema is a medical procedure in which a liquid or gas is injected into the colon through the rectum, usually with the intent of stimulating a bowel movement

Indeed, their results showed slow motor function, measured by finger tapping speed, and anhedonia, the inability to feel pleasure and a common characteristic of depression, coincided with high levels of glutamate and myo-inositol in the basal ganglia

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Zhang Y-H, Wang D-W, Xu S-F, Zhang S, Fan Y-G, Yang Y-Y, et al

Antimycin is a known inhibitor of the mitochondrial electron transport chain (ETC) complex III inhibiting OXPHOS