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Although liver transplantation offers a curative approach for B6 non-respondents, it carries notable challenges, including surgical risks, the need for prolonged immunosuppression and limited donor availability

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The calculated trends for the two reactions are consistent with the fact that no ortho -Se = N substituted phenol (or only small amount of ortho -S = N substituted phenol) was obtained for these two types of reactions

35,36 Finally, DEX has been reported to promote resolution of inflammation through activation of so-called specialised pro-resolving lipid mediators

mBio 12 , e03457-20 (2021)