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doi: 10.1016/j.micinf.2003.09.012 22 OwenCA

346 Moreover, mounting evidence has shown that NAD + -dependent sirtuins can extend the lifespan of yeast, worms, flies and mice and alleviate many diseases of aging-related pathologies

Diabetes 61 , 888896 (2012)

Furthermore, in the case of amyloid fibrils made of two or more protofilaments, inter-molecular correlations may be originating from axial contacts (along the fibril), or contacts that are made with the neighboring protofilaments