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In the second group were found a considerably higher percentage of eyes with a final VA of 20/200 or worse, regardless whether the eyes had undergone laser treatment or not

After multi-week interventions, this front-end advantage consolidates as higher autophagic/mitophagic flux, often coupled to optimized mitochondrial dynamics (OPA1/MFN2 upregulation, DRP1 normalization), thereby promoting biogenesis and functional recovery (Lu et al., 2022)