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SKU: 16867960072
Price: 27.65 USD
Availability: InStock
Rating: 4.5886000000000005 (14 reviews)

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Description

10.1016/j.lfs.2022.120306 67 GibalaM

demonstrated that the combination of the lysosome disruptor siramesine with the tyrosine kinase inhibitor lapatinib resulted in the ferroptotic death of breast cancer cells

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Because LC is easily transported through the bloodbrain barrier via the organic cation/carnitine transporter novel family member 2 (OCTN2), its plasma and cerebrospinal fluid concentrations increase after oral administration (Sarzi-Puttini et al