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By restoring a physiological pressure gradient between the venous system and the subarachnoid space, venous sinus stentingA minimally invasive surgery during which a metallic mesh in the shape of a tube (stent) is placed in the sinus

Bioorg Med Chem 25:126131

Homocysteine-lowering therapy with supplemental B vitamins (folic acid, vitamin B 6 , and vitamin B 12 ) may be particularly useful in lowering the risk of stroke but appears to have little utility in the prevention of other cardiovascular events

doi:10.1074/jbc.M109641200 Imai H, Masayasu H, Dewar D, Graham DI, Macrae IM (2001) Ebselen protects both gray model of focal and white matter in a rodent cerebral ischemia

Finally, the fragments are placed into a bone preparation device that utilizes vacuum ultrasonic high-pressure sterilization, and different solutions (Liquid A: 3% hydrochloric acid, Liquid B: 10% hydrogen peroxide, and Liquid C: 80% ethanol) are used according to the manufacturing method