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For both these poses at diverse pH, a static thermodynamic quantification was carried out using MM-GBSA, which was 49.20 and 56.93 Kcal/mol, respectively

Boon, P., Moors, I., De Herdt, V

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In ischemic AKI models, ferulic acid reduced inflammatory cell infiltration and alleviated capillary congestion, thereby improving renal microcirculatory flow and oxygenation, independent of direct tubular cytoprotection (Zhou et al