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In dermatological contexts, the most clinically relevant gene targets include: COL1A1 and COL3A1 upregulation increases procollagen type I and III synthesis, directly counteracting age-related collagen depletion

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doi: 10.1080/15548627.2016.1187366 13 SinghMAroraHLNaikRJoshiSSonawaneKSharmaNKet al