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Description

Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis -[amminedichloro(2-methylpyridine)] platinum(II) (AMD473)

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The clearest signals are in eye disease using a drop formulation, such as neurotrophic keratopathy and dry eye [3] [4] , plus short-term infusion safety data in healthy volunteers [6]

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At late stages, it develops into geographic atrophy (GA), a chronic and progressive degeneration of retinal cells

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Biochem Biophys Res Commun 112:5560 Lebo R, Kredich N (1978) Inactivation of human -glutamylcysteine synthetase by cystamine

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J Biol Chem 281(1):6979 Boysen G, Jamshidi-Parsian DMA et al (2019) Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice

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