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Perilipin-null mice also display a significant resistance to diet-induced obesity (78, 106, 127) that is explained, at least in part, by increased beta-oxidation of fatty acids, the products of lipolysis (106), following from a compensatory induction of genes involved in lipid and energy metabolism and a downregulation of genes involved in lipid biosynthesis (20)

The protein CD38 (CLUSTER OF DIFFERENTIATION 38) is a multifunctional enzyme that degrades NAD and modulates cellular NAD homeostasis

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Leukemia 29:20392049 Richardson P, Perrot A, San-Miguel J, Beksac M, Spicka I, Leleu X et al (2021) Updates from ICARIA-MM, a phase 3 study of isatuximab (Isa) plus pomalidomide and low-dose dexamethasone (Pd) versus Pd in relapsed and refractory multiple myeloma (RRMM)