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It appears that AC can suppress MMP-1 expression in cultured human epidermal keratinocytes, an effect that is probably mediated by modulation of MAPK/AP-1 and I-/NF- signaling pathways (Gao et al

Acta Paediatr Scand, 77(5): 663-670

270 Owing to the nonspecific prodromal symptoms and its extremely rapid progressive nature, most of our knowledge about FM was obtained from postmortem examination