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A validation of these pockets observed in FBDD by XRD (with notably exception of evident functional sites that can be derived from prior enzymological knowledge) with respect to druggability usually requires follow-up experiments as typically carried out in F2L and medicinal chemistry studies 90

Then gently invert the vial several times or until all the lyophilized product dissolves

doi: 10.2174/1871527322666230412105711