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10.1038/ncomms9468 60

PCOS is the most widespread cause of female infertility in developed countries

Epithalon may be integrated into comprehensive longevity programs alongside other evidence-based interventions such as nutritional optimization, exercise protocols, hormone balancing, and other therapeutic approaches

doi: 10.1183/13993003.00432-2015 18 Castaeda-GarcaA.BlzquezJ.Rodrguez-RojasA

Moreover, the gut microbiota and its associated metabolites promote the differentiation and function of anti-inflammatory macrophages, Treg cells, CD4 + CD8 + regulatory cells, IL-10 + and/or IL-35 + B regulatory cells, as well as IL-22-producing innate lymphoid cells 3 (ILC3), which are involved in maintaining the gut mucosal homeostasis (Su et al., 2022) and protecting the kidneys (Su et al., 2022)