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Pharmacogenomics 19 (5), 495511

A delicate balance between ROS and antioxidants (The cellular redox state) is needed for T-cell receptor signalling to launch an effective immune response

doi: 10.1095/biolreprod.105.040360

In vivo efficacy of the nanoparticle after 18 days showed that there was less than 2-fold increase in tumor volume which was lower than the volume increase of mice treated with free mitoxantrone or nanoparticle without iRGD