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Factors such as trauma, nutritional deficiencies, irritable bowel disorders, leaky gut, microbiome dysbiosis, and immune dysregulation can all contribute to the generation of ROS, leading to tissue damage and ulcer formation

55 Other studies have demonstrated that YAP sensitizes HCC cells to ferroptosis by transcriptionally upregulating arachidonate lipoxygenase 3 leading to an increase of lipid peroxidation, 56 and O-GlcNAcylation increases the ferroptosis sensitivity of HCC cells through the YAP/transferrin receptor pathway, 57 suggesting that YAP may be an effective biomarker for predicting the response of HCC cells to ferroptotic induction

Ketogenic diet for the treatment and prevention of dementia: a review

307 , E553E562 (2014)

Can hormonal changes affect melanin levels in the skin