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34 In summary, unlike in clinical studies, and, although transient biological changes can be detected, disc trauma without loss of nucleus tissue or nucleus herniation and without endplate impairment so far has not shown to promote disc degeneration in biological models

Further, we clarify that if a hospital has encoded a payer-specific negotiated charge in the MRF as a dollar amount, and that dollar amount represents the full payer-specific negotiated charge that is not further modified by a percentage or algorithm, the hospital would not be required to encode the allowed amounts

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A splicing mutation has been held responsible for Japanese acatalasemia I where a substitution of a guanine residue with adenine residue at position 5 of intron 4 disturbed the splicing pattern of the RNA product producing a defective protein [137]

Studies including mixed populations were considered only if data for SCD or MCI could be separately extracted