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Baseline characteristics were collected at admission and included patients age, gender, weight, height, type of diabetes, creatinine clearance (CrCl), eGFR, serum osmolality, AG, bicarbonate level, electrolytes, A1c, pH, ketones, and serum glucose level

Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNF) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)

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These long half-lives are the result of fatty acid conjugation and albumin binding, which delay renal and enzymatic clearance

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