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The percentage of aberrations was calculated as follows: An Olympus CX- 41 research microscope (100X objective) was used to observe the chromosome structure

The combination of all these synthesis effects, occurring simultaneously through overlapping pathways, produces the skin quality improvements that clinical trials document

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Flow cytometry quantitative analysis showed that the total ROS level was 41.2% in the HO group and remained almost unchanged in the g-CN group (39.8%), whereas the Ru SA+AC group exhibited a significant reduction in intracellular ROS content (12.2%) (Fig

Determination of mitochondrial reactive oxygen species production The production of reactive oxygen species (ROS) in the mitochondrial matrix was determined as a time-dependent increase in the fluorescence intensity of selective MitoSOX (Life Technologies, Pleasanton, CA, USA) dye in the cells exposed to tested therapeutics using flow cytometry (BD LSRII, BD Biosciences, San Jose, CA, USA)