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Nature 353 , 864866 (1991)

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This selectivity profile matched GHRH, which also does not stimulate the hypothalamic-pituitary-adrenal (HPA) axis

Researchers analyze how the activation of the ghrelin receptor induces an influx of extracellular calcium through voltage-gated channels, paired with the release of calcium from internal stores, to physically drive the exocytosis of growth hormone vesicles