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So that the

Since SARS-CoV-2 activates mitochondrial ROS-mediated feedback loops that produce long-term changes in the redox status and endothelial function of the host, leading to cardiovascular disease and lung injury (Chang et al., 2021), and endothelial cells are key players in inflammatory pathologies, such as acute respiratory distress syndrome, thrombosis, and atherosclerosis

The majority of ADRs are non-immunologically mediated

This damage can accelerate the aging process and increase the risk of chronic diseases such as cardiovascular issues, diabetes, and even neurodegenerative conditions like Alzheimers