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Furthermore, Reprogramming the metabolism, Erythroid 2-Related Factor two (Nrf2) is a nuclear factor that directly alters intermediate metabolism and organizes genes that generate protective proteins that direct the breakdown and reform of impacted macromolecules under stressful circumstances (110)

In addition to stool analysis, other non-invasive methods such as urine and exhaled breath tests have also been employed clinically to detect alterations in gut microbial metabolites in patients with CRC

[DOI] [PubMed] [Google Scholar] 38.Faghih Dinevari M, Jafarzadeh F, Jabbaripour Sarmadian A, Abbasian S, Nikniaz Z, Riazi A