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Inflammatory synovitis in OA (a form of periarticular tissue damage) encompasses various abnormalities, such as synovial lining hyperplasia, infiltration of macrophages, pannus formation, and fibrosis (Sellam and Berenbaum, 2010)

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Investigations of apoptosis dysregulation and chemoresponses in chronic lymphocytic leukemia

A subsequent study by these investigators revealed that during mammary embryogenesis Notch signaling prevents the generation of basal precursors, and cells expressing active NOTCH1 exclusively give rise to the ER (Sca1-/CD133-) lineage at any developmental stage from mouse embryonic day 13.5 to postpartum day 3 53