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Analysis of ALT (alanine aminotransferase, a serum marker of liver damage) revealed a strong increase in Atp7b / mice, while Atp7b / :Prnp / animals exhibited significantly lower ALT values (Fig

What I'm looking for through all of this is where you are in the Charcot process

doi: 10.4049/jimmunol.174.6.3650 26 YamazakiSMutaTTakeshigeK

Results Screening for genes that promote copper toxicity in a cell model of Wilson disease To find new genes that might be targeted for reduction of Cu toxicity in Wilson disease we employed genome-wide shRNA screening in ATP7B-KO HepG2 cells, a bona fide WD cell model 12,13

Gragert, L., Madbouly, A., Freeman, J