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However, excessive activation of Drp1 leads to overactive mitochondrial fission, producing dysfunctional mitochondria that produces large amounts of ROS (Ruegsegger et al., 2018) (Figure 2)

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A typical example is the over production of a substance, 15 HPETE (15-hydroperoxy eicosatetraenoic acid), from activated macrophages

Acetyl-L-Carnitine (ALCAR) A mitochondrial metabolite, acetyl-L-carnitine protects the brain from

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