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The evidence for an association between gut microbiota and hypertension emanates from studies in murine models showing that rats lacking normal gut flora experience elevated blood pressure [29, 30]

P H Shetty acknowledges support from the Department of Forensic Medicine and Toxicology, Kasturba Medical College, Mangalore, Manipal Academy Of Higher Education, Manipal, India

2285-C CHOLESTEROL-ASSOCIATED LOCUS EHBP1 PROTECTS AGAINST NASH FIBROSIS Fanglin Ma and Bishuang Cai, Icahn School of Medicine at Mount Sinai Background: Elevated hepatic cholesterol content is frequently seen in human NASH and high-cholesterol diets have been found to promote NASH progression in mouse models

This hypothesis is further supported by the current dataset indicating that CACNA1F is expressed at levels insufficient to support functional channel formation [65]